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    What is Wegovy®?

    Wegovy® is a once-weekly weight loss injection that’s easy to use with pre-filled pens for self-administration. It contains semaglutide, a GLP-1 hormone mimic that helps control appetite and keep you feeling fuller for longer, making it easier to lose weight.

    For the best results, Wegovy® should be used alongside a healthy, lower-calorie diet and regular exercise.

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    Who is eligible for Wegovy®?

    You may be eligible for a Wegovy prescription if you meet one of the following criteria:

    • A BMI of 30 or higher
    • A BMI of 27 or higher with a weight-related medical condition, such as high blood pressure or cardiovascular disease.

    Wegovy isn't suitable for everyone. You should not take Wegovy if you are:

    • allergic to any of its ingredients.
    • pregnant or planning to become pregnant.
    • breastfeeding.

    If you have pancreas or heart problems, your doctor will evaluate whether Wegovy is a good fit for you. A prescription will only be provided if it is deemed safe and suitable for your medical condition.

    How it Works

    Wegovy’s active ingredient, semaglutide, mimics the natural GLP-1 hormone that regulates appetite. By targeting receptors in the brain, it helps curb cravings and reduce hunger. Combined with a lower-calorie diet and regular physical activity, Wegovy helps promote effective weight loss.

    How Effective Is Wegovy®?

    Clinical trials show that Wegovy® (2.4 mg dose) leads to significant weight loss when combined with a healthy diet and exercise:

    • ✅ 85% of people lost at least 5% of their body weight
    • ✅ 66% lost at least 10%
    • ✅ 50% lost 15% or more

    On average, Wegovy® users lost 14.9% of their body weight over 68 weeks compared to 2.4% in the placebo group.

    How to Take Wegovy®

    Wegovy® is injected once a week under the skin, with or without food. Try to take it at the same time each week for consistency. Each Wegovy® pen contains 4 doses, lasting 4 weeks before you need a new pen.

    Always double-check that you have the correct dose and medication before injecting, especially if you use other injectable treatments.

    How to Inject Wegovy®

    Follow the patient information leaflet for full instructions, including diagrams, and any advice from your doctor. The steps below are a general guide:

    • ✅ Check your medication – Ensure you have the correct dose and that the liquid is clear and colourless.
    • ✅ Prepare the pen - Remove the cap and attach a new needle for each weekly dose.
    • ✅ Perform a flow check (only the first time using a new pen).
    • ✅ Set the dose - Turn the dose selector until it matches your prescription.
    • ✅ Choose an injection site - Stomach, upper legs, or upper arms (rotate sites weekly).
    • ✅ Inject at a straight angle - Ensure you can see the dose counter while injecting.
    • ✅ Dispose of the needle - Place it in a sharps bin and store the pen safely for future doses.
    • ✅ Log your dose - Keep track of when you last took Wegovy® and set a reminder for the next one.

    Where to Inject Wegovy®

    Wegovy® should be injected under the skin (subcutaneous injection) in one of these areas:

    • ✓ Stomach (abdomen)
    • ✓ Upper legs (thighs)
    • ✓ Upper arms (upper arms)

    Rotate injection sites each week to prevent irritation or soreness.

    Wegovy® Dosage Schedule

    Wegovy® comes in 5 dose strengths, starting at a low dose and gradually increasing every 4 weeks to help your body adjust and reduce side effects.

    Wegovy dosage schedule

    ⚠️ Important: Do not increase your dose beyond 2.4 mg per week. Always follow your prescribed dosage plan.

    What Happens If I Stop Taking Wegovy®?

    Wegovy® is not addictive, so you won’t experience withdrawal symptoms if you stop taking it. However, stopping suddenly may lead to weight regain, so it’s best to speak with our clinical team before discontinuing the treatment.

    What If I Miss a Dose of Wegovy®?

    • If it’s been 5 days or less → Take the missed dose as soon as you remember and continue with your usual schedule.
    • If it’s been more than 5 days → Skip the missed dose and wait until your next scheduled injection. Do not take a double dose.

    If you miss multiple doses, speak with our clinical team, as you may need to restart at a lower dose to minimize side effects.

    Wegovy® Side Effects

    Most side effects improve as your body adjusts to the medication.

    Common Side Effects:

    • Headache
    • Nausea or vomiting
    • Diarrhea or constipation
    • Tiredness or weakness
    • Stomach pain
    • Bloating, burping, or gas
    • Reactions at the injection site (redness, swelling, or soreness)

    Serious Side Effects (Seek Medical Help Immediately)

    • Diabetic retinopathy complications (vision problems in people with diabetes)
    • Pancreatitis (severe stomach or back pain)
    • Kidney or bladder stones (painful urination, lower abdomen or back pain)
    • Severe allergic reaction (swelling, breathing difficulty—call 999)
    • Bone fractures
    • Bowel obstruction (severe constipation, vomiting, stomach pain)

    Wegovy® Drug Interactions

    • Diabetes medications (e.g., insulin, sulfonylureas) → May increase risk of low blood sugar.
    • Other GLP-1 receptor agonists (e.g., Mounjaro®, Saxenda®) → Taking them together can be dangerous.

    Always inform your doctor about any medications you take before starting Wegovy®.

    Who Should NOT Take Wegovy®?

    • 🚫 Pregnant or breastfeeding women
    • 🚫 People with a BMI below 30 (unless they have a weight-related condition)
    • 🚫 Anyone with a history of pancreatitis, severe heart failure, or severe gastroparesis
    • 🚫 People with allergies to semaglutide or any ingredients in Wegovy®
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FAQs about Wegovy® injections
How to Store Wegovy® +
  • Before Opening: Store in a fridge (2°C to 8°C), away from the cooling element. Do not freeze - if frozen, discard the pen.
  • After Opening:
    • In the fridge: Keep between 2°C and 8°C.
    • Out of the fridge: Keep at room temperature (below 30°C) for up to 6 weeks.
  • Keep away from children and store in original packaging to protect from light.
Where Can I Buy Wegovy® in the UK? +
You can request Wegovy® from PillTime’s weight loss service once you have completed the simple assessment. Always buy from a trusted provider and avoid unverified sellers.
Can I Get Wegovy® on the NHS? +
Yes, but access is limited. You may get it via:
  • Referral to a Tier 3 Weight Management Service (waiting times vary).
  • Prescription from a GP or Pharmacist (availability is still limited).
Can Wegovy® Improve Heart Health? +
Yes! Wegovy® is approved to reduce heart attack and stroke risk in overweight adults with heart conditions. It can lower the risk of major cardiovascular events by 20%.
How Long Do You Take Wegovy®? +
Wegovy® is safe for long-term use and has been studied up to 4 years. You don't have to stop at goal weight unless advised by your doctor.
How Long Does Wegovy® Take to Work? +
Effects can begin in days, but full results take weeks. Best outcomes occur after reaching the maintenance dose for a few months.
How to Get a Prescription for Wegovy® +
  • Online: Complete a medical questionnaire via PillTime or another service. Must meet BMI/medical criteria.
  • NHS: Ask your GP for a referral to a weight management service.